DYNAMIC CHANGES IN MYOFIBROBLASTS AFFECT THE CARCINOGENESIS AND PROGNOSIS OF BLADDER CANCER ASSOCIATED WITH TUMOR MICROENVIRONMENT REMODELING

Dynamic Changes in Myofibroblasts Affect the Carcinogenesis and Prognosis of Bladder Cancer Associated With Tumor Microenvironment Remodeling

Bladder cancer (BLCA) is a tumor that possesses significant heterogeneity, and the tumor microenvironment (TME) plays an important role in the development of BLCA.The TME chiefly consists of tumor cells and tumor-infiltrating immune cells admixed with stromal components.Recent studies have revealed that stromal components, especially cancer-associa

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Motion Planning of Nonholonomic Mobile Manipulators with Manipulability Maximization Considering Joints Physical Constraints and Self-Collision Avoidance

The motion of nonholonomic mobile manipulators (NMMs) is inherently constrained by joint limits, joint velocity limits, self-collisions and singularities.Most motion planning algorithms consider some Cargo Trousers of the aforementioned constraints, however, a unified framework to deal with all of them is lacking.This paper proposes a motion planni

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